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최권영

Kwonyoung Choi

박사

​환경생물공학전공

정보

  • 연구실 : 혜강관 724호

  • 연구실번호(교내) : 1825

  • ​이메일 : kychoi@ajou.ac.kr

학력

  • 2011. 08 서울대학교 박사

  • 2006. 02 서울대학교 학사

경력

  • 2011-2012 / Post Doctor, Institute of Molecular Biology and Genetics, Seoul National University

  • 2012-2014 / Research Scientist, Department of Chemical and Biomolecular Engineering, University of California, Los Angeles

  • 2014-2017 / Assistant Professor, Department of Environmental Engineering, Ajou University

  • 2018-Present / Associate Professor, Department of Environmental Engineering, Ajou University

연구성과

 

2020년

81.HyunA Park, Gyuyeon Park, Wooyoung Jeon, Jung-Oh Ahn, Yung-Hun Yang, Kwon-Young Choi, "Production of blue-colored polyhydroxybutyrate (PHB) by one-pot production and coextraction of indigo and PHB from recombinant Escherichia coli", 173, 107889, Dyes and Pigments, 2020

80. HyunA Park, Gyuyeon Park, Wooyoung Jeon, Jung-Oh Ahn, Yung-Hun Yang, Kwon-Young Choi, "Whole-cell biocatalysis using cytochrome P450 monooxygenases for biotransformation of sustainable bioresources (fatty acids, fatty alkanes, and aromatic amino acids)", 130, 107329, Bioelectrochemistry, 2020

79. EJ Kim, D Seo, KY Choi, "Bioalcohol production from spent coffee grounds and okara waste biomass by engineered Bacillus subtilis", 10 (1), 167-173, Biomass Conversion and Biorefinery, 2020

78. KY Choi, "A review of recent progress in the synthesis of bio-indigoids and their biologically assisted end-use applications", 108570, Dyes and Pigments, 2020

77. HA Park, I Yang, M Choi, KS Jang, JC Jung, KY Choi, "Engineering of melanin biopolymer by co-expression of MelC tyrosinase with CYP102G4 monooxygenase: Structural composition understanding by 15 tesla FT-ICR MS analysis",157, 107530, Biochemical Engineering Journal, 2020

76. Tae-Rim Choi, Hun-Suk Song, Yeong-Hoon Han, Ye-Lim Park, Jun Young Park, Su-Yeon Yang, Shashi Kant Bhatia, Ranjit Gurav, Hyun Joong Kim, Yoo Kyung Lee, Kwon Young Choi, Yung-Hun Yang, "Enhanced tolerance to inhibitors of Escherichia coli by heterologous expression of cyclopropane-fatty acid-acyl-phospholipid synthase (cfa) from Halomonas socia", 1-10, Bioprocess and Biosystems Engineering, 2020

75. Jeongchan Lee, Joonwon Kim, Hyun Kim, Eun-Jung Kim, Hee-Jin Jeong, Kwon-Young Choi, Byung-Gee Kim, "Characterization of a Tryptophan 6‐Halogenase from Streptomyces albus and Its Regioselectivity Determinants", ChemBioChem, 2020

74. DS Min, S Choi, E Oh, J Lee, CG Lee, K Choi, S Jung, "Numerical modelling for effect of water curtain in mitigating toxic gas release", 103972, Journal of Loss Prevention in the Process Industries 63, 2020

73. Hun-Suk Song, Jong-Min Jeon, Shashi Kant Bhatia, Tae-Rim Choi, Sun Mi Lee, Sol Lee Park, Hye Soo Lee, Jeong-Jun Yoon, Jungoh Ahn, Hongweon Lee, Christopher J Brigham, Kwon-Young Choi, Yung-Hun Yang, "Enhanced isobutanol production by co-production of polyhydroxybutyrate and cofactor engineering", Journal of biotechnology, 2020

72. KY Choi, "Discoloration of indigo dyes by eco-friendly biocatalysts: Recent progress", 108749, Dyes and Pigments, 2020

71. Ye-Lim Park, Yeong-Hoon Han, Hun-Suk Song, Jun-Young Park, Shashi Kant Bhatia, Ranjit Gurav, Kwon-Young Choi, Yun-Gon Kim, Yung-Hun Yang, "Effects of osmolytes on salt resistance of Halomonas socia CKY01 and identification of osmolytes-related genes by genome sequencing", Journal of Biotechnology, 2020

70. SY Kim, YH Yang, KY Choi, "Bioconversion of Plant Hydrolysate Biomass into Biofuels Using an Engineered Bacillus subtilis and Escherichia coli Mixed-whole Cell Biotransformation", 477-484, Biotechnology and Bioprocess Engineering 25 (3), 2020

69. SA Park, SY Ahn, KY Choi, "Functional Microbial Pigments Isolated from Chryseobacterium and Deinococcus species for Bio-paint Application", 394-402, Biotechnology and Bioprocess Engineering 25 (3), 2020

68. C Park, S Kim, Y Kwon, C Jeong, Y Cho, CG Lee, S Jung, KY Choi, J Lee, "Pyrolysis of Polyethylene Terephthalate over Carbon-Supported Pd Catalyst", 496, Catalysts 10 (5), 2020

67. HA Park, KY Choi, "α, ω-Oxyfunctionalization of C12 alkanes via whole-cell biocatalysis of CYP153A from Marinobacter aquaeolei and a new CYP from Nocardia farcinica IFM10152", 156, 107524, Biochemical Engineering Journal, 2020

66. W Kim, J Lee, KY Choi, BG Kim, J Kim, "Regioselective Biotransformation of Phloretin Using Streptomyces avermitilis MA4680" ,25 (2), 272-278, Biotechnology and Bioprocess Engineering,  2020

65. D Seo, KY Choi, "Heterologous production of pyomelanin biopolymer using 4-hydroxyphenylpyruvate dioxygenase isolated from Ralstonia pickettii in Escherichia coli", 107548, Biochemical Engineering Journal, 2020

64. Won-Suk Song, Seong-Min Kim, Sung-Hyun Jo, Jae-Seung Lee, Hyo-Jin Jeon, Byoung Joon Ko, Kwon-Young Choi, Yung-Hun Yang, Yun-Gon Kim, "Multi-omics characterization of the osmotic stress resistance and protease activities of the halophilic bacterium Pseudoalteromonas phenolica in response to salt stress",10 (40), 23792-23800, RSC Advances, 2020

2019년

63. Shashi Kant Bhatia, Ranjit Gurav, Tae-Rim Choi, Hye-Rim Jung, Soo-Yeon Yang, Yu-Mi Moon, Hun-Suk Song, Jong-Min Jeon, Kwon-Young Choi, Yung-Hun Yang, "Bioconversion of plant biomass hydrolysate into bioplastic (polyhydroxyalkanoates) using Ralstonia eutropha 5119", 271, 306-3015, Bioresource technology, 2019 

62. Seyun Namgung, Hyun A Park, Joonwon Kim, Pyung-Gang Lee, Byung-Gee Kim, Yung-Hun Yang, Kwon-Young Choi, "Ecofriendly one-pot biosynthesis of indigo derivative dyes using CYP102G4 and PrnA halogenase", 162, 80-88, Dyes and Pigments, 2019

61. Ranjit Gurav, Shashi Kant Bhatia, Tae-Rim Choi, Hye-Rim Jung, Soo-Yeon Yang, Hun-Suk Song, Ye-Lim Park, Yeong-Hoon Han, Jun-Young Park, Yun-Gon Kim, Kwon-Young Choi, Yung-Hun Yang, "Bioconversion of barley straw lignin into biodiesel using Rhodococcus sp. YHY01", 289, 121704, Bioresource technology, 2019

60. Soo-Yeon Ahn, Mira Choi, Da-woon Jeong, SeoA Park, HyunA Park, Kyoung-Soon Jang, Kwon-Young Choi, "Synthesis and chemical composition analysis of protocatechualdehyde-based novel melanin dye by 15T FT-ICR: high dyeing performance on soft contact lens", 160, 546-554, Dyes and Pigments, 2019

59. Ranjit Gurav, Shashi Kant Bhatia, Tae-Rim Choi, Hye-Rim Jung, Soo-Yeon Yang, Hun-Suk Song, Ye-Lim Park, Yeong-Hoon Han, Jun-Young Park, Yun-Gon Kim, Kwon-Young Choi, Yung-Hun Yang, "Chitin biomass powered microbial fuel cell for electricity production using halophilic Bacillus circulans BBL03 isolated from sea salt harvesting area", 130, 107329, Bioelectrochemistry, 2019

 

2018년

 

52. Jang S., Gang H., Kim B.-G., Choi K.-Y.* “FCS and ECH dependent production of phenolic aldehyde and melanin pigment from L-tyrosine in

Escherichia coli”, 112, 59-64, Enzyme and Microbial Technology, 2018

51. Jung E., Park B.G., Yoo H.-W., Kim J., Choi K.-Y., Kim B.-G.” Semi-rational engineering of CYP153A35 to enhance ω-hydroxylation activity toward palmitic acid.”, 102(1), 269-277, Applied Microbiology and Biotechnology, 2018

2017년

50. Park M.S., Choi K.-Y.* “Investigation of liquid phase ammonia removal efficiency by chemo-biological process of zeolites and klebsiella pneumonia sp.”, 28(6), 685-690, Applied Chemistry for Engineering, 2017

49. Lee P.-G., Kim J., Kim E.-J., Lee S.-H., Choi K.-Y., Kazlauskas R.J., Kim B.-G.” Biosynthesis of (-)-5-Hydroxy-equol and 5-Hydroxy-dehydroequol from Soy Isoflavone, Genistein Using Microbial Whole Cell Bioconversion”, 12(11), 2883-2890, ACS Chemical Biology, 2017

48. Sudheer P.D.V.N., Yun J., Chauhan S., Kang T.J., Choi K.-Y.*” Screening, expression, and characterization of Baeyer-Villiger monooxygenases for the production of 9-(nonanoyloxy)nonanoic acid from oleic acid”, 22(6), 717-724, Biotechnology and Bioprocess Engineering, 2017

47. Johnson J., Sudheer P.D.V.N., Yang Y.-H., Kim Y.-G., Choi K.-Y.*,” Hydrolytic activities of hydrolase enzymes from halophilic microorganisms”, 22(4), 450-461, Biotechnology and Bioprocess Engineering, 2017

46. Gang H., Lee D., Choi K.-Y.*, Kim H.-N., Ryu H., Lee D.-S., Kim B.-G., “Development of High Performance Polyurethane Elastomers Using Vanillin-Based Green Polyol Chain Extender Originating from Lignocellulosic Biomass”, 5(6), 4582-4588, ACS Sustainable Chemistry & Engineeering, 2017

45. Kim H.-J., Jang S., Kim J., Yang Y.-H., Kim Y.-G., Kim B.-G., Choi K.-Y.*” Biosynthesis of indigo in Escherichia coli expressing self-sufficient CYP102A from Streptomyces cattleya”, 140, 29-35, Dyes & Pigments, 2017

44. Kim K.-J., Kim Y.-W., Park H.-G., Hwang C.-H., Park I.Y., Choi K.-Y., Yang Y.-H., Kim Y.H., Kim Y.-G.,” A MALDI-MS-based quantitative glycoprofiling method on a 96-well plate platform”, 46, 29-35, Journal of Industrial and Engineering Chemistry, 2017

43. Ham K.J., Park M.S., Choi K.-Y.*,” Investigation of liquid phase formaldehyde removal efficiency by enzymatic formaldehyde dehydrogenase and catalytic chemisorption reactions” 28(1), 50-60, Applied Chemistry for Engineering, 2017

42. Kim K.-J., Park H.-G., Hwang C.-H., Ann D.-H., Song W.-S., Choi K.-Y., Yang Y.-H., Park S.Y., Kim Y.-G.,” Quantitative targeted metabolomics for 15d-deoxy-Δ12, 14-PGJ2 (15d-PGJ2) by MALDI-MS”, 22(1), 100-106, Biotechnology and Bioprocess Engineering, 2017

41. Kim J., Seo H.-M., Bhatia S.K., Song H.-S., Kim J.-H., Jeon J.-M., Choi K.-Y., Kim W., Yoon J.-J., Kim Y.-G., Yang Y.-H., “Production of itaconate by whole-cell bioconversion of citrate mediated by expression of multiple cis-aconitate decarboxylase (cadA) genes in Escherichia coli.”, 7, 39768, Scientific Reports, 2017

 

2016년

40. Jung E., Park B.G., Ahsan M.M., Kim J., Yun H., Choi K.-Y., Kim B.-G., “Production of ω-hydroxy palmitic acid using CYP153A35 and comparison of cytochrome P450 electron transfer system in vivo”, 100(24), 10375-10384, Applied Microbiology and Biotechnology, 2016

39. Kim JH, Kim HJ, Kim YH, Jeon JM, Song HS, Kim JY, No SY, Shin JH, Choi KY, Park KM, Yang YH., “Functional study of lysine decarboxylases from Klebsiella pneumoniae in Escherichia coli and application of whole cell bioconversion for cadaverine production., Journal of Microbiology and Biotechnology, 2016

38. Jung D, Kim EJ, Jung E, Kazlauskas RJ, Choi KY*, Kim BG, “Production of p-hydroxybenzoic acid from p-coumaric acid by Burkholderia glumae BGR1”, Biotechnology and Bioengineering, 113 (7), 1493-1503, Applied Microbiology and Biotechnology, 2016

37. Seo HM, Jeon JM, Lee JH, Song HS, Joo HB, Park SH, Choi KY, Kim YH, Park K, Ahn J, Lee H, Yang YH, “Combinatorial application of two aldehyde oxidoreductases on isobutanol production in the presence of furfural”, 43 (1), 37-44, Journal of Industrial Microbiology and Biotechnology, 2016

 

2015년

36. Choi KY*, “Non-enzymatic PLP-dependent oxidative deamination of amino acids induces higher alcohol synthesis”, Biotechnolgy and Bioprcess Engineering, 20 (6), pp. 988-994, 2015

35. Jeon JM, Park H, Seo HM, Kim HJ, Yi DH, Kim JH, Lee JH, Choi KY, Sang BI, and Yang YH, “Isobutanol production from engineered Shewanella oneidensis MR-1”, Biotechnology and Bioprocess Engineering 20 (6), pp. 988-994, 2015

34. Kim HJ, Kim YH, Shin JH, Shashi KB, Seo HM, Choi KY, ParK KM, and Yang YH, “Optimization of direct lysine decarboxylase biotransformation for cadaverine production with whole cell biocatalysts at high substrate concentration”, Journal of Industrial & Engineering Chemistry, 25(7),  1108-1113, 2015

33. Kanagavel D, Saravanan PN, Bae DH, Baek WH, Choi KY, Yun HD, Temperature sensing using red fluorescent protein, Biotechnology and Bioprocess Engineering, 20, 67-72, 2015

32. Sung C, Jung E, Choi KY, Kim MS, Kim J, Kim EJ, and Kim BG, “Production of ω-hydroxy palmitic acids from glucose by genetic engineered Escherichia coli.”, Applied Microbiology and Biotechnology, 99 (16), pp. 6667-6676, 2015

31. Ko SK, Choi KY*, Yang YH, and Kim BG, “Rational design and directed evolution of CYP102A1 (BM3) for regio-specific hydroxylation of isoflavone” , Biotechnology and Bioprocess Engineering, 20 (2), 4, pp. 225-233, 2015

30. Yang YH, Kim BG, Choi KY*, “Synthesis of 3’-ortho-dihydroxy isoflavone by regio-selectivity driven evolution of CYP102D1”, Enzyme and Microbial Technology, 71, 20-27, 2015

29. Kim HJ, Choi YK, Jeon HJ, Shashi  KB, Kim YH, Kim YG, Choi KY, Kim HJ, Lee SH, Lee YK, and Yang YH, “Growth-promotion of Chlorella vulgaris by modification of nitrogen source composition with symbiotic bacteria, Microbacterium sp. HJ1", Biomass and Bioenergy,74, 214-219 2015

28. Jung E, Choi KY, Jung DH, Yun HD, Kim BG, Hydroxylation of Mammalian Lignan Enterodiol by Cytochrome P450s in Actinomycetes sp., Korean Journal of Chemical Engineering, 32(3), 471-477, 2015

 

2014년

27. Kim YH, Park BS, Bhaia SK, Seo HM, Jeon JM, Kim HJ, Yi DH, Choi KY, Park HY, Yang YH, “Production of rapamycin in Streptomyces hygroscopicus from glycerol based media optimization by systemic methodology”, Journal of Microbiology and Biotechnology, 24(10):1319-1326 ,2014

26. Choi KY*, Jung EO, Yang YH, Hyungdon Yun, and Kim BG, “Engineering class I cytochrome P450s by gene fusion with NADPH-dependent reductase and S. avermitilis host development for daidzein biotransformation”, Applied Microbiology and Biotechnology, 98(19):8191-200, 2014

25. Choi KY*, David G. Wernick, Christine A. Tat and James C. Liao, “Consolidated conversion of protein waste into biofuels and ammonia using Bacillus subtilis”, Metabolic Engineering,23:53-61, 2014

24. Pandey BP, Lee N, Choi KY, Kim JW, Kim EJ and Kim BG, “Identification of electron transfer protein ferredoxin and ferredoxin reductase for CYP105D7 activity towards dadizein from Streptomyces avermitilis MA4680”, Applied Microbiology and Biotechnology,  98(11):5009-17, 2014

23. Rajesh T, Jeon JM, Song E, Park HM, Seo HM, Kim HJ, Yi DH, Kim YH, Choi KY, Kim YG, Park HY, Lee YK, Yang YH, “Putative role of a Streptomyces coelicolor-derived α-mannosidase in deglycosylation and antibiotic production”, Applied Biochemistry and Biotechnology, Feb , 172(3):1639-51, 2014

 

2013년

 

22. David G. Wernick, Choi KY, Christine A. Tat, Jimmy G. La Fontaine Rivera, and James C. Liao, “The extreme obligate alkaliphile Bacillus marmarensis DSM21297: Genome sequence and characterization reveal its application for ammonia reclamation and biorefining”, Genome Announcements (ASM), 27;1(6), 2013

21. Rajesh T, Kim YH, Choi YK, Jeon JM, Kim HJ, Park SH, Park HY, Choi KY, Kim H, Kim HJ, Lee SH, and Yang YH, “Identification of functional characterization of an α-amylase with broad temperature and pH stability from Paenibacillus sp.”, Applied Biochemistry and Biotechnology, May; 170(2):359-69, 2013

20. Jeon JM, Choi HW, Yoo GC, Rajesh T, Choi YK, Choi KY, Park HY, Park SH, Kim  YG, Kim HJ, Lee SH and Yang YH, “New mixture composition of organic solvents for efficient extraction of lipids from Chlorella vulgaris”, Biomass & Bioenergy, Dec;59:279-284, 2013

19. Rajesh T, Jeon JM, Kim YH, Ki, HJ, Yi DH, Park SH, Choi KY, Kim YG, Kim J, Jung S, Park HY and Yang YH, “Functional analysis of the gene SCO1782 encoding Streptomyces hemolysin (S-hemolysin) in Streptomyces coelicolor M145”, Toxicon, Sep;71:159-65, 2013

18. Choi KY*, Jung EO, Yang YH, Romas J. Kazlauskas and Kim BG, “Development of colorimetric HTS assay of cytochrome P450 for ortho-specific hydroxylation and engineering of CYP102D1 with enhanced catalytic activity and regioselectivity”, ChemBioChem, Jul 8;14(10):1231-8, 2013

17. Choi KY*, Jung EO, Yang YH, Kim BG, “Production of a novel O-methyl-isoflavone by regioselective sequential hydroxylation and O-methylation reactions in Streptomyces avermitilis host system.” Biotechnology and Bioengineering, 110(10), 2591-99, 2013

16. Rajesh T, Sung C, Kim H, Song E, Park HY, Jeon JM, Yoo D, Kim HJ, Kim YH, Choi KY, Song KG and Yang YH, “Phosphorylation of chloroamphenicol by a recombinant protein Yhr2 from Streptomyces avermitilis MA4680”, Bioorganic & Medicinal Chemistry Letters, June 15;23(12):3614-9, 2013

15. Rajesh T, Kim YH, Choi YK, Jeon JM, Kim HJ, Park SH, Park HY, Choi KY, Kim H, Kim HJ, Lee SH, Yang YH, “Identification and Functional Characterization of an α-Amylase with Broad Temperature and pH Stability from Paenibacillus sp.”, Applied Biochemistry and Biotechnology, May; 170(2):359-369, 2013

14. Song E, Rajesh T, Lee BR, Kim EJ, Jeon JM, Park SH, Park HY, Choi KY, Kim YG, Yang YH, Kim BG, “Deletion of an architectural unit, leucyl aminopeptidase (SCO2179), in Streptomyces coelicolor increases actinorhodin production and sporulation.”, Applied Microbiology and Biotechnology, Aug;97(15):6823-33, 2013

13. Choi KY*, Kim HJ, Jung DH, Jung JY, Jung E, Yang YH, Kim BG, Oh MK, “Transcriptomic study for screening genes involved in the oxidative bioconversions of Streptomyces avermitilis.”, Bioprocess Biosystems Engineering, Mar 9, On-line published, 2013(contributed equally)

12. Jung DH, Choi W, Choi KY, Jung E, Yun H, Kazlauskas RJ, Kim BG, “Bioconversion of p-coumaric acid to p-hydroxystyrene using phenolic acid decarboxylase from B. amyloliquefaciens in biphasic reaction system.”, Applied Microbiology and Biotechnology. Feb;97(4):1501-11, 2013

 

2012년

 

11. Choi KY*, Jung E, Jung DH, Pandey BP, Lee N, Yun H, Park HYand Kim BG, “Novel iron-sulfur containing NADPH-reductase from Nocardia farcinica IFM10152 and fusion construction with CYP51 lanosterol demethylase”, Biotechnology and Bioengineering, 109(3):630-636, 2012

10. Choi KY*, Jung E, Jung DH, Park HY and Kim BG, “Engineering of daidzein 3’-hydroxylase P450 enzyme into catalytically artificial self-sufficient CYP”, Microbial Cell Factories, 11(81), 2012

9. Choi KY*, Jung E, Jung DH, Park HY, Lee N and Kim BG, “Cloning, expression and characterization of CYP102D1, a self-sufficient P450 monooxygenases from Streptomyces avermitilis”, FEBS Journal, 279(9):1650-1662, 2012

2011년

 

8.  Pandey BP, Lee N, Choi KY, Jung E, Jeong DH and Byung-Gee Kim "Screening of Bacterial Cytochrome P450s responsible for regiospecific hydroxylation of (iso)flavonoids" Enzyme and Microbial Technology. 48(4-5):386-392, 2011

7. Chung YH, Song JW, Choi KY, Yoon JW, Yang KM and Park JB, “Cloning, Expression, and Characterization of P450 Monooxygenase CYP102H1 from Nocardia farcinica”, Journal of The Korean Society for Applied Biological Chemistry, 55(2):386-392, 2011

 

2010년

 

6.  Pandey BP, Roh C, Choi KY, Lee N, Kim EJ, Ko S, Kim T, Yun H and Kim BG, “Regioselective Hydroxylation of Daidzein Using P450 (CYP105D7) from Streptomyces avermitilis MA4680", Biotechnology and Bioengineering, 105(4):697-704, 2010

5.  Park JS, Kim DH, Shim JS, Kim JS, Choi KY, Kim BG, Kim DH and Kim HK, "7,8,4'-Trihydroxyisoflavone from Fermented Soybean Food and Its Biological Activity" J.Soc.Cosmet. Scientists Korea, 36(3):221-226, 2010

4.  Choi KY*, Park HY, Kim BG. "Characterization of bi-functional CYP154 from Nocardia farcinica IFM10152 in the O-dealkylation and ortho-hydroxylation of formononetin", Enzyme and Microbial Technology 47(7):327-334, 2010

 

2009년

 

3.  Choi KY*, Kim TJ, Koh SK, Roh CH, Pandey BP, Lee N, Kim BG, "A-ring ortho-specific monohydroxylation of daidzein by cytochrome P450s of Nocardia farcinica IFM10152" Biotechnology journal, 4(11):1586-1595, 2009

2.  Roh C, Choi KY, Pandey BP, Kim BG, "Hydroxylation of daidzein by CYP107H1 from Bacillus subtilis 168" Journal of Molecular Catalysis B: Enzymatic, 59:248-253, 2009

1. Roh C. Seo SH, Choi KY,  Cha M, Pandey BP, Kim JH, Park JS, Kim DH, Chang IS and Kim BG, "Regioselective hydroxylation of isoflavones by Streptomyces avermitilis MA-4680" The Journal of Bioscience and Bioengineering, 108(1):41-46, 2009

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